Clinical significance of myocardial work parameters after acute myocardial infarction

نویسندگان

چکیده

Abstract Background To date, there is little data regarding the clinical significance of myocardial work (MW) parameters after a stable period following acute infarction (AMI). Purpose investigate additional prognostic value MW AMI. Methods Between 2018 and 2020, 244 patients admitted in cardiac intensive care unit university hospital for AMI were included. One-month AMI, comprehensive transthoracic echocardiography (TTE) was performed to assess function. Patients then followed major events (ME): cardiovascular death, heart failure unplanned coronary revascularisation. Results At 1 month, half population symptomatic (NYHA≥II), medical therapy almost optimized (ACEi/ARB 95.5%, beta-blockers 96.3%, DAPT 94.7% statins 97.1%). After median follow-up 681 [IQR 538–840] days, ME occurred 26 (10.7%). presenting older (65.5±14.2 vs. 58.1±12.1 years, P=0.005) with higher prevalence hypertension (65.4 36.2%, P=0.004), more impaired LV function as assessed by left ventricular ejection fraction (LVEF) (P=0.07), global longitudinal strain (GLS) (P=0.03) or (P=0.01 efficiency (GWE)), greater LA dilations (P=0.06 LVEDVi P=0.03 LAVi). adjustment, GWE only TTE parameter independently associated long-term occurrence (P=0.02). A <91% selected identify at risk (HR 95% CI) = 2.94 (1.36–6.35), P=0.0041) (Figure & 2). Conclusion Lower month rates. can improve post-AMI patient stratification. Funding Acknowledgement Type funding sources: None.

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2022

ISSN: ['2634-3916']

DOI: https://doi.org/10.1093/eurheartj/ehac544.015